The role of supercritical fluids in the fractionation pretreatments of a wheat bran-based biorefinery (Review)

Wheat bran is a very interesting feedstock for lignocellulosic biorefineries. The recovery of proteins, oil and phytochemicals can be integrated with the fractionation of polysaccharides and lignin, adding value to a multi-product biorefinery concept. After reviewing the work previously reported in the literature concerning the use of sc-CO2 and subcritical and supercritical water, the present […]

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Production Of β-Glucan Scaffolds By Supercritical Fluids

In the fields of medical and pharmaceutical research, aerogels are attaining great attention, both for tissue regeneration and/or drug delivery, because they afford good properties for this purpose: provide mechanical support, allow cellular interactions, are biodegradable and can also be used to deliver active compounds to the area of the implant. Besides, they must be […]

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[Paper]: Using different natural origin carriers for development of epigallocatechin gallate (EGCG) solid formulations with improved antioxidant activity by PGSS-drying

Epigallocatechin gallate (EGCG) is the catechin with the highest antioxidant activity present in green tea. Nevertheless, due its low bioavailability, it is necessary to develop EGCG formulations capable of improving its stability resulting in increased bioavailability and thus higher biological activity of this catechin (e.g. antioxidant activity). The purpose of this work was the formulation […]

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[Paper]: Production of water soluble quercetin formulations by pressurized ethyl acetate-in-water emulsion technique

Quercetin is a strong antioxidant flavonoid with several bioactive properties such as anti-inflammatory and anticarcinogenic activities, becoming an interesting compound to be incorporated into pharmaceutical, cosmetic or food products. However, these applications are limited by the low bioavailability of this flavonoid. Quercetin is poorly soluble in aqueous media, such as gastrointestinal fluids, being also degraded […]

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[Award] CFS – Jerry King Poster Award: Encapsulation of fungicide to enhance its penetration through the cell wall of the fungi

One of our PhD students, Marta Salgado, won the Jerry King Poster Award to the best poster presented by a graduate student, sponsored by Critical Fluid Symposia, in the recent 14th European Meeting on Supercritical Fluids. All presented posters were evaluated by the Poster Judging Committee, chaired by Jerry King and composed of members of […]

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