[Thesis]: Bioproducts Processing By SFEE: Application For Liquid And Solid Quercetin Formulations

Dr. Gyorgy Levai  defended past Monday 28 th November his PhD thesis at the University of Valladolid. The thesis was directed by Dr. Ángel Martín and Dr. Soraya Rodriguez Rojo from the High Pressure Processes Group and it has the mention of International PhD because of his secondment in the Department of Experimental Thermodynamics in Ruhr-University of Bochum, under the […]

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[Paper]: Using different natural origin carriers for development of epigallocatechin gallate (EGCG) solid formulations with improved antioxidant activity by PGSS-drying

Epigallocatechin gallate (EGCG) is the catechin with the highest antioxidant activity present in green tea. Nevertheless, due its low bioavailability, it is necessary to develop EGCG formulations capable of improving its stability resulting in increased bioavailability and thus higher biological activity of this catechin (e.g. antioxidant activity). The purpose of this work was the formulation […]

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Efficient production of soy-bean lecithin – pluronic L64® encapsulated quercetin particles in nanometric scale using SFEE and PGSS drying processes

Quercetin occurs in various fruits, vegetables and many other food components. According to preliminary studies, it has strong antioxidant-, antiviral-, antibacterial-, antihistaminic-, and anti-inflammatory effect. Due to these properties, quercetin is a highly promising material against a wide variety of diseases, including cancer. A major limitation for the clinical application of quercetin is its low […]

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[Course] WineSense Spring School 2016

Valladolid, 18-22 April 2016 The WineSense Spring School 2016 held at the University of Valladolid was a big success!  Over 40 students and 20 speakers took part in a whole week of first-class lectures, team work, activities and networking. The WSS was organized by the High Pressure Processes Group as part of the training activities […]

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[Paper]: Production of water soluble quercetin formulations by pressurized ethyl acetate-in-water emulsion technique

Quercetin is a strong antioxidant flavonoid with several bioactive properties such as anti-inflammatory and anticarcinogenic activities, becoming an interesting compound to be incorporated into pharmaceutical, cosmetic or food products. However, these applications are limited by the low bioavailability of this flavonoid. Quercetin is poorly soluble in aqueous media, such as gastrointestinal fluids, being also degraded […]

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Production of encapsulated quercetin particles in sub-micrometric scale

Quercetin is a bioflavonoid with a strong antioxidant-, antiviral-, antibacterial-, antihistaminic-and anti-inflammatory effect. Due to these properties, quercetin is a highly promising material against a wide variety of diseases, including cancer. A major limitation for the clinical application of quercetin is its low bioavailability that makes it necessary to administe in high doses (50 mg/kg). […]

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