Development Of Novel Fungicide Formulations To Enhance Their Penetration Through The Cell Wall Of The Fungi

Figure 1: Formation of fungicide particles from oil-in-water emulsions
Figure 1: Formation of fungicide particles from oil-in-water emulsions

Nowadays it is necessary to look for new formulations of fungicides that allow us to reduce the use of toxic substances in an effort to preserve the environment, as well as to avoid the formation of resistant strains to traditional fungicides. With this purpose, new naturally produced substances are being formulated, such as resveratrol as active compound, since it is reported to have antifungal properties, and β-glucans as encapsulating material, because they can improve the penetration of the active compound through the cell wall of the fungi, taking into account that many fungi contain β-glucans in their structure. The different formulation methods used comprise both formation of oil-in-water emulsions, e.g. by high shear or ultrasound emulsification, and solid particles (Figure 1), by conventional (spray-drying) or supercritical methods (supercritical anti-solvent and particles from gas saturated solutions-drying).

Marta Salgado – Project PIP 063147181

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